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Recombinant Human ATP-sensitive inward rectifier potassium channel 14 (KCNJ14), Truncated

ACP07134

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP07134 Target NameKCNJ14
Target Synonymsinwardly rectifying subfamily J member 14, KCNJ14; IRK4; ATP-sensitive inward rectifier potassium channel 14; Inward rectifier K(+ channel Kir2.4; IRK-4; Potassium channelFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9UNX9
Background Information
  • Uniprot Id

    Q9UNX9

  • Target Species

    Human

  • Target Name

    KCNJ14

  • Target Full Name

    ATP-sensitive inward rectifier potassium channel 14

  • Target Function

    Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ14 gives rise to low-conductance channels with a low affinity to the channel blockers Barium and Cesium.

  • Target Subcellular Location

    Membrane; Multi-pass membrane protein.

  • Target Protein Families

    Inward rectifier-type potassium channel (TC 1.A.2.1) family, KCNJ14 subfamily

  • Target Tissue Specificity

    Expressed preferentially in retina.

  • Target Synonyms

    KCNJ14; IRK4; ATP-sensitive inward rectifier potassium channel 14; Inward rectifier K(+ channel Kir2.4; IRK-4; Potassium channel, inwardly rectifying subfamily J member 14

Inquire Recombinant Human ATP-sensitive inward rectifier potassium channel 14 (KCNJ14), Truncated Now



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