Recombinant Human Beta-casein (CSN2)

Uniprot Id

P05814

Target Species

Human

Target Name

CSN2

Target Full Name

Beta-casein

Target Function

Important role in determination of the surface properties of the casein micelles.

Target Subcellular Location

Secreted.

Target Protein Families

Beta-casein family

Target Tissue Specificity

Mammary gland specific. Secreted in milk.

Target Synonyms

Beta-casein; CASB; CASB_HUMAN; Casein beta; CSN 2; Csn2

Target Background

This gene is a member of the beta casein family. There are two types of casein protein, beta (encoded by this gene) and kappa, both of which are secreted in human milk. Beta casein is the principal protein in human milk and the primary source of essential amino acids for a suckling infant. Beta and kappa casein proteins acting together form spherical micelles which bind within them important dietary minerals, such as calcium and phosphorous. In addition, the C-terminal 14 aa of the protein has antimicrobial activity, especially in preterm milk, displaying antibacterial activity against S. aureus and Y. enterocolitica. Alternative splicing results in multiple transcript variants.