Recombinant Human Beta-galactoside alpha-2,6-sialyltransferase 1 (ST6GAL1), Truncated

Uniprot Id

P15907

Target Species

Human

Target Name

ST6GAL1

Target Full Name

Beta-galactoside alpha-2,6-sialyltransferase 1

Target Function

Transfers sialic acid from CMP-sialic acid to galactose-containing acceptor substrates.

Target Subcellular Location

Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted. Note=Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.

Target Protein Families

Glycosyltransferase 29 family

Target Synonyms

ST6GAL1; SIAT1; Beta-galactoside alpha-2,6-sialyltransferase 1; Alpha 2,6-ST 1; B-cell antigen CD75; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1; ST6Gal I; ST6GalI; Sialyltransferase 1

Target Background

This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Alternative splicing results in multiple transcript variants.