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Recombinant Human Brain-specific angiogenesis inhibitor 2 (BAI2), Truncated

ACP06285

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Specifications

Cat.No	ACP06285	Target Name	ADGRB2
Target Synonyms	ADGRB2; BAI2Adhesion G protein-coupled receptor B2; Brain-specific angiogenesis inhibitor 2	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O60241

Background Information

Uniprot Id

O60241
Target Species

Human
Target Name

ADGRB2
Target Full Name

Adhesion G protein-coupled receptor B2
Target Function

Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT-signaling pathway, a transcription factor, via the G-protein GNAZ. Involved in angiogenesis inhibition.
Target Subcellular Location

Cell membrane; Multi-pass membrane protein.
Target Protein Families

G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
Target Tissue Specificity

Strongly expressed in brain. Also detected in heart, thymus, skeletal muscle, and different cell lines.
Target Synonyms

ADGRB2; BAI2Adhesion G protein-coupled receptor B2; Brain-specific angiogenesis inhibitor 2
Target Background

This gene encodes a a seven-span transmembrane protein that is thought to be a member of the secretin receptor family. The encoded protein is a brain-specific inhibitor of angiogenesis. The mature peptide may be further cleaved into additional products (PMID:20367554). Alternative splicing results in multiple transcript variants.

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Recombinant Human Brain-specific angiogenesis inhibitor 2 (BAI2), Truncated

Specifications

Immunogen Information

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