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Recombinant Human Brain-specific angiogenesis inhibitor 3 (BAI3), Truncated

ACP06284

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Specifications

Cat.No	ACP06284	Target Name	ADGRB3
Target Synonyms	BAI3; BAI3_HUMAN; Brain-specific angiogenesis inhibitor 3; dJ91B17.1 (brain specific angiogenesis inhibitor 3); KIAA0550	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O60242

Background Information

Uniprot Id

O60242
Target Species

Human
Target Name

ADGRB3
Target Full Name

Adhesion G protein-coupled receptor B3
Target Function

Receptor that plays a role in the regulation of synaptogenesis and dendritic spine formation at least partly via interaction with ELMO1 and RAC1 activity. Promotes myoblast fusion through ELMO/DOCK1.
Target Subcellular Location

Cell membrane; Multi-pass membrane protein.
Target Protein Families

G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
Target Tissue Specificity

Strongly expressed in brain. Also detected in heart. Reduced expression in some glioblastoma cell lines.
Target Synonyms

BAI3; BAI3_HUMAN; Brain-specific angiogenesis inhibitor 3; dJ91B17.1 (brain specific angiogenesis inhibitor 3); KIAA0550
Target Background

This p53-target gene encodes a brain-specific angiogenesis inhibitor, a seven-span transmembrane protein, and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities, and may also play a role in angiogenesis.

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Recombinant Human Brain-specific angiogenesis inhibitor 3 (BAI3), Truncated

Specifications

Immunogen Information

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