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| Cat.No | ACP13815 | Target Name | KCTD12 |
|---|---|---|---|
| Target Synonyms | 13orf2; BTB/POZ domain-containing protein KCTD12; KCD12_HUMAN; KCTD12; KIAA1778; PFET1; Pfetin; potassium channel tetramerisation domain containing 12 USA ; Predominantly fetal expressed T1 domain | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 2-325 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96CX2 |
|---|
Uniprot Id
Q96CX2
Target Species
Human
Target Name
KCTD12
Target Full Name
BTB/POZ domain-containing protein KCTD12
Target Function
Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization.
Target Subcellular Location
Cell junction, synapse, presynaptic cell membrane. Cell junction, synapse, postsynaptic cell membrane.
Target Tissue Specificity
Present in a variety of fetal organs, with highest expression levels in the cochlea and brain and, in stark contrast, is detected only at extremely low levels in adult organs, such as brain and lung.
Target Synonyms
13orf2; BTB/POZ domain-containing protein KCTD12; KCD12_HUMAN; KCTD12; KIAA1778; PFET1; Pfetin; potassium channel tetramerisation domain containing 12 USA ; Predominantly fetal expressed T1 domain
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