Recombinant Human C-X-C motif chemokine 6 (CXCL6)

Uniprot Id

P80162

Target Species

Human

Target Name

CXCL6

Target Full Name

C-X-C motif chemokine 6

Target Function

Chemotactic for neutrophil granulocytes. Signals through binding and activation of its receptors (CXCR1 and CXCR2). In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram-negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7).

Target Subcellular Location

Secreted.

Target Protein Families

Intercrine alpha (chemokine CxC) family

Target Synonyms

C X C motif chemokine 6; Chemokine (C X C motif) ligand 6; Chemokine alpha 3; CKA 3; CKA-3; CKA3; CXCL 6; CXCL6; CXCL6_HUMAN; GCP 2; GCP-2; Granulocyte chemotactic protein 2; N-processed variant 3; SCYB6; Small inducible cytokine B6; Small inducible cytokine subfamily B (Cys X Cys) member 6; Small inducible cytokine subfamily B (Cys X Cys) member b; Small-inducible cytokine B6

Target Background

The protein encoded by this gene is a member CXC chemokine family. The encoded protein is a chemotactic for neutrophil granulocytes and has antibacterial action against gram-negative and gram-positive bacteria. This gene and other members of the CXC chemokine gene family form a gene cluster in a region of chromosome 4q.