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| Cat.No | ACP10912 | Target Name | CHST7 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NS84 |
|---|
Uniprot Id
Q9NS84
Target Species
Human
Target Name
CHST7
Target Full Name
Carbohydrate sulfotransferase 7
Target Function
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues. Preferentially acts on mannose-linked GlcNAc. Also able to catalyze the transfer of sulfate to position 6 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Also acts on core 2 mucin-type oligosaccharide and N-acetyllactosamine oligomer with a lower efficiency. Has weak or no activity toward keratan sulfate and oligosaccharides containing the Galbeta1-4GlcNAc. Catalyzes 6-O-sulfation of beta-benzyl GlcNAc but not alpha- or beta-benzyl GalNAc
Target Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein.
Target Protein Families
Sulfotransferase 1 family, Gal/GlcNAc/GalNAc subfamily
Target Tissue Specificity
Widely expressed. Highly expressed in heart, spleen, liver and ovary. Expressed at lower level in brain, placenta, thyroid, spinal cord and peripheral blood leukocytes. Not expressed in adult skin.
Target Synonyms
CHST7Carbohydrate sulfotransferase 7; EC 2.8.2.-; EC 2.8.2.17; Chondroitin 6-sulfotransferase 2; C6ST-2; Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 5; GST-5; N-acetylglucosamine 6-O-sulfotransferase 4; GlcNAc6ST-4; Gn6st-4
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