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Recombinant Human Carbonic anhydrase 5A, mitochondrial (CA5A)

ACP23335

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP23335 Target NameCA5A
Target SynonymsCA5A; CA5Carbonic anhydrase 5A; mitochondrial; EC 4.2.1.1; Carbonate dehydratase VA; Carbonic anhydrase VA; CA-VAFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range39-305
Protein LengthFull Length of Mature ProteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP35218
Background Information
  • Uniprot Id

    P35218

  • Target Species

    Human

  • Target Name

    CA5A

  • Target Full Name

    Carbonic anhydrase 5A, mitochondrial

  • Target Function

    Reversible hydration of carbon dioxide. Low activity.

  • Target Involvement

    Hyperammonemia due to carbonic anhydrase VA deficiency (CA5AD)

  • Target Subcellular Location

    Mitochondrion.

  • Target Protein Families

    Alpha-carbonic anhydrase family

  • Target Research Area

    Metabolism

  • Target Synonyms

    CA5A; CA5Carbonic anhydrase 5A; mitochondrial; EC 4.2.1.1; Carbonate dehydratase VA; Carbonic anhydrase VA; CA-VA

  • Target Background

    Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VA is localized in the mitochondria and expressed primarily in the liver. It may play an important role in ureagenesis and gluconeogenesis. CA5A gene maps to chromosome 16q24.3 and an unprocessed pseudogene has been assigned to 16p12-p11.2.

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