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Recombinant Human Cdc42 effector protein 3 (CDC42EP3)

ACP10104

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Specifications

Cat.No	ACP10104	Target Name	CDC42EP3
Target Synonyms	CDC42EP3; BORG2; CEP3Cdc42 effector protein 3; Binder of Rho GTPases 2; MSE55-related Cdc42-binding protein	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-254
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9UKI2

Background Information

Uniprot Id

Q9UKI2
Target Species

Human
Target Name

CDC42EP3
Target Full Name

Cdc42 effector protein 3
Target Function

Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts.
Target Subcellular Location

Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton.
Target Protein Families

BORG/CEP family
Target Tissue Specificity

Highly expressed in the heart and weakly in the brain.
Target Synonyms

CDC42EP3; BORG2; CEP3Cdc42 effector protein 3; Binder of Rho GTPases 2; MSE55-related Cdc42-binding protein
Target Background

This gene encodes a member of a small family of guanosine triphosphate (GTP) metabolizing proteins that contain a CRIB (Cdc42, Rac interactive binding) domain. Members of this family of proteins act as effectors of CDC42 function. The encoded protein is involved in actin cytoskeleton re-organization during cell shape changes, including pseudopodia formation. A pseudogene of this gene is found on chromosome 19. Alternative splicing results in multiple transcript variants.

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Recombinant Human Cdc42 effector protein 3 (CDC42EP3)

Specifications

Immunogen Information

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