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| Cat.No | ACP07259 | Target Name | CLN6 |
|---|---|---|---|
| Target Synonyms | CLN6; Ceroid-lipofuscinosis neuronal protein 6; Protein CLN6 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NWW5 |
|---|
Uniprot Id
Q9NWW5
Target Species
Human
Target Name
CLN6
Target Full Name
Ceroid-lipofuscinosis neuronal protein 6
Target Involvement
Ceroid lipofuscinosis, neuronal, 6 (CLN6); Ceroid lipofuscinosis, neuronal, 4A (CLN4A)
Target Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum.
Target Synonyms
CLN6; Ceroid-lipofuscinosis neuronal protein 6; Protein CLN6
Target Background
This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.
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