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| Cat.No | ACP15059 | Target Name | CCDC28A |
|---|---|---|---|
| Target Synonyms | CCDC28A; C6orf80; Coiled-coil domain-containing protein 28A; CCRL1AP | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-274 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8IWP9 |
|---|
Uniprot Id
Q8IWP9
Target Species
Human
Target Name
CCDC28A
Target Full Name
Coiled-coil domain-containing protein 28A
Target Involvement
A chromosomal aberration involving CCDC28A has been identified in acute leukemias. Translocation t(6;11)(q24.1;p15.5) with NUP98. The chimeric transcript is an in-frame fusion of NUP98 exon 13 to CCDC28A exon 2. Ectopic expression of NUP98-CCDC28A in mouse promotes the proliferative capacity and self-renewal potential of hematopoietic progenitors and rapidly induced fatal myeloproliferative neoplasms and defects in the differentiation of the erythro-megakaryocytic lineage.
Target Synonyms
CCDC28A; C6orf80; Coiled-coil domain-containing protein 28A; CCRL1AP
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