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| Cat.No | ACP08928 | Target Name | CNKSR2 |
|---|---|---|---|
| Target Synonyms | CNKSR2; CNK2; KIAA0902; KSR2Connector enhancer of kinase suppressor of ras 2; Connector enhancer of KSR 2; CNK homolog protein 2; CNK2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 650-800aa |
| Mol Weight | 19.1kD | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8WXI2 |
|---|
Uniprot Id
Q8WXI2
Target Species
Human
Target Name
CNKSR2
Target Full Name
Connector enhancer of kinase suppressor of ras 2
Target Function
May function as an adapter protein or regulator of Ras signaling pathways.
Target Subcellular Location
Cytoplasm. Membrane; Peripheral membrane protein.
Target Protein Families
CNKSR family
Target Research Area
Signal Transduction
Target Synonyms
CNKSR2; CNK2; KIAA0902; KSR2Connector enhancer of kinase suppressor of ras 2; Connector enhancer of KSR 2; CNK homolog protein 2; CNK2
Target Background
This gene encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. This gene product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene.
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