Recombinant Human Constitutive coactivator of PPAR-gamma-like protein 1 (FAM120A), Truncated

Uniprot Id

Q9NZB2

Target Species

Human

Target Name

FAM120A

Target Full Name

Constitutive coactivator of PPAR-gamma-like protein 1

Target Function

May participate in mRNA transport in the cytoplasm. Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses.

Target Subcellular Location

Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Translocates to plasma membrane upon ultraviolet exposure.

Target Protein Families

Constitutive coactivator of PPAR-gamma family

Target Tissue Specificity

Ubiquitously expressed. Highly expressed in scirrhous-type gastric cancer tissues compared with normal gastric mucosa (at protein level).

Target Synonyms

C9orf10; Chromosome 9 open reading frame 10; Constitutive coactivator of PPAR gamma like protein 1; Constitutive coactivator of PPAR-gamma-like protein 1; DNA polymerase transactivated protein 5; DNA polymerase transactivated protein 1; DNAPTP1; DNAPTP5; F120A_HUMAN; FAM120A; Family with sequence similarity 120A; Hypothetical protein LOC23196; KIAA0183; LOC23196; MGC111527; MGC133257; OSSA; Oxidative stress-associated Src activator; Protein FAM120A

Target Background

Enables RNA binding activity. Located in cytosol.