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| Cat.No | ACP11267 | Target Name | DOCK5 |
|---|---|---|---|
| Target Synonyms | DOCK5Dedicator of cytokinesis protein 5 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H7D0 |
|---|
Uniprot Id
Q9H7D0
Target Species
Human
Target Name
DOCK5
Target Full Name
Dedicator of cytokinesis protein 5
Target Function
Guanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen.
Target Subcellular Location
Cytoplasm. Cell membrane.
Target Protein Families
DOCK family
Target Synonyms
DOCK5Dedicator of cytokinesis protein 5
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