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| Cat.No | ACP13494 | Target Name | DOCK6 |
|---|---|---|---|
| Target Synonyms | Dedicator of cytokinesis protein 6; Dock6; DOCK6_HUMAN | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96HP0 |
|---|
Uniprot Id
Q96HP0
Target Species
Human
Target Name
DOCK6
Target Full Name
Dedicator of cytokinesis protein 6
Target Function
Acts as guanine nucleotide exchange factor (GEF) for CDC42 and RAC1 small GTPases. Through its activation of CDC42 and RAC1, may regulate neurite outgrowth.
Target Involvement
Adams-Oliver syndrome 2 (AOS2)
Target Subcellular Location
Cytoplasm. Cytoplasm, perinuclear region. Note=Mainly located near the cell surface.
Target Protein Families
DOCK family
Target Tissue Specificity
Widely expressed. Expressed at low level in spleen, cerebellum, hippocampus and in substantia nigra.
Target Synonyms
Dedicator of cytokinesis protein 6; Dock6; DOCK6_HUMAN
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