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| Cat.No | ACP21195 | Target Name | BRINP1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 20-761 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O60477 |
|---|
Uniprot Id
O60477
Target Species
Human
Target Name
BRINP1
Target Full Name
BMP/retinoic acid-inducible neural-specific protein 1
Target Function
Inhibits cell proliferation by negative regulation of the G1/S transition. Mediates cell death which is not of the classical apoptotic type and regulates expression of components of the plasminogen pathway.
Target Subcellular Location
Cytoplasm.
Target Protein Families
BRINP family
Target Tissue Specificity
Highly expressed in brain. Weakly expressed in heart, lung, skeletal muscle, kidney, thymus, prostate, testis and small intestine.
Target Synonyms
BMP/retinoic acid-inducible neural-specific protein 1; BRINP1; DBC1; DBC1_HUMAN; DBCCR1 ; Deleted in bladder cancer protein 1; Deleted in bladder cancer protein 1 precursor; FAM5A; IB3089A; Protein FAM5A
Target Background
This gene is located within a chromosomal region that shows loss of heterozygosity in some bladder cancers. It contains a 5' CpG island that may be a frequent target of hypermethylation, and it may undergo hypermethylation-based silencing in some bladder cancers.
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