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| Cat.No | ACP05640 | Target Name | DSE |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9UL01 |
|---|
Uniprot Id
Q9UL01
Target Species
Human
Target Name
DSE
Target Full Name
Dermatan-sulfate epimerase
Target Function
Converts D-glucuronic acid to L-iduronic acid (IdoUA) residues. Plays an important role in the biosynthesis of the glycosaminoglycan/mucopolysaccharide dermatan sulfate.
Target Involvement
Ehlers-Danlos syndrome, musculocontractural type 2 (EDSMC2)
Target Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Microsome membrane; Multi-pass membrane protein.
Target Protein Families
Dermatan-sulfate isomerase family
Target Tissue Specificity
Ubiquitously expressed with higher expression in kidney and ovary and lower expression in brain, colon and thymus. Also expressed in renal cell carcinomas, brain tumors, and in a part of melanomas and adenocarcinomas from organs other than the breast. Exp
Target Synonyms
Chondroitin glucuronate 5 epimerase; Chondroitin-glucuronate 5-epimerase; Dermatan sulfate epimerase; Dermatan-sulfate epimerase; DS epimerase; DSE; DSE_HUMAN; DSEPI; OTTHUMP00000040406; SART 2; SART-2; Squamous cell carcinoma antigen recognized by T cells 2; Squamous cell carcinoma antigen recognized by T-cells 2
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