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| Cat.No | ACP15827 | Target Name | DET1 |
|---|---|---|---|
| Target Synonyms | DET1; DET1 homolog; De-etiolated-1 homolog | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-550 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q7L5Y6 |
|---|
Uniprot Id
Q7L5Y6
Target Species
Human
Target Name
DET1
Target Full Name
DET1 homolog
Target Function
Component of the E3 ubiquitin ligase DCX DET1-COP1 complex, which is required for ubiquitination and subsequent degradation of target proteins. The complex is involved in JUN ubiquitination and degradation.
Target Subcellular Location
Nucleus.
Target Protein Families
DET1 family
Target Tissue Specificity
Highly expressed in the ovary, some lymphoid organs and resting leukocytes.
Target Synonyms
DET1; DET1 homolog; De-etiolated-1 homolog
Target Background
Enables ubiquitin ligase-substrate adaptor activity and ubiquitin protein ligase binding activity. Involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination; and protein-containing complex assembly. Part of Cul4A-RING E3 ubiquitin ligase complex.
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