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| Cat.No | ACP12314 | Target Name | ADAM33 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9BZ11 |
|---|
Uniprot Id
Q9BZ11
Target Species
Human
Target Name
ADAM33
Target Full Name
Disintegrin and metalloproteinase domain-containing protein 33
Target Involvement
Asthma (ASTHMA)
Target Subcellular Location
Membrane; Single-pass type I membrane protein.
Target Tissue Specificity
Expressed in all tissues, except liver, with high expression in placenta, lung, spleen and veins.
Target Research Area
Cell Biology
Target Synonyms
A disintegrin and metalloprotease 33; A disintegrin and metalloproteinase domain 33; ADA33_HUMAN; ADAM 33; ADAM metallopeptidase domain 33; ADAM33; C20orf153; Disintegrin and metalloproteinase domain-containing protein 33; Disintegrin and reprolysin metalloproteinase family protein; DJ964F7.1; DKFZp434K0521; FLJ35308; FLJ36751; Metalloprotease disintegrin; MGC149823; MGC71889; PRO1891; UNQ873
Target Background
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness. Alternative splicing results in multiple transcript variants encoding different isoforms.
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