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Recombinant Human DNA-directed RNA polymerase I subunit RPA43 (TWISTNB)

ACP17561

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP17561 Target NameTWISTNB
Target SynonymsDNA directed RNA polymerase I subunit RPA43; DNA-directed RNA polymerase I subunit RPA43; RPA43; RPA43_HUMAN; TWIST neighbor; Twist neighbor protein; TwistnbFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-338
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ3B726
Background Information
  • Uniprot Id

    Q3B726

  • Target Species

    Human

  • Target Name

    POLR1F

  • Target Full Name

    DNA-directed RNA polymerase I subunit RPA43

  • Target Function

    DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Through its association with RRN3/TIF-IA may be involved in recruitment of Pol I to rDNA promoters.

  • Target Subcellular Location

    Nucleus, nucleolus.

  • Target Protein Families

    Eukaryotic RPA43 RNA polymerase subunit family

  • Target Tissue Specificity

    Widely expressed. Expressed in all fetal and adult tissues tested, with highest expression in fetal lung, liver, and kidney, and low expression in all adult tissues.

  • Target Synonyms

    DNA directed RNA polymerase I subunit RPA43; DNA-directed RNA polymerase I subunit RPA43; RPA43; RPA43_HUMAN; TWIST neighbor; Twist neighbor protein; Twistnb

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