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Recombinant Human Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (DAPP1)

ACP09816

Number
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Specifications


Cat.No ACP09816 Target NameDAPP1
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range1-280Protein LengthFull length protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9UN19
Background Information
  • Uniprot Id

    Q9UN19

  • Target Species

    Human

  • Target Name

    DAPP1

  • Target Full Name

    Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide

  • Target Function

    May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.

  • Target Subcellular Location

    Cytoplasm. Membrane; Peripheral membrane protein. Note=Membrane-associated after cell stimulation leading to its translocation.

  • Target Tissue Specificity

    Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.

  • Target Synonyms

    B cell adapter molecule of 32 kDa; B lymphocyte adapter protein Bam32; B-cell adapter molecule of 32 kDa; BAM32; DAPP1; DAPP1_HUMAN; DKFZp667E0716; Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide; Dual adaptor of phosphotyrosine and 3 phosphoinositides; hDAPP1

  • Target Background

    Enables phosphatidylinositol-3, 4, 5-trisphosphate binding activity and phosphatidylinositol-3, 4-bisphosphate binding activity. Predicted to be involved in signal transduction. Located in plasma membrane.

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