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| Cat.No | ACP09903 | Target Name | CDC14A |
|---|---|---|---|
| Target Synonyms | CDC14A; Dual specificity protein phosphatase CDC14A; EC 3.1.3.16; EC 3.1.3.48; CDC14 cell division cycle 14 homolog A | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-594 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9UNH5 |
|---|
Uniprot Id
Q9UNH5
Target Species
Human
Target Name
CDC14A
Target Full Name
Dual specificity protein phosphatase CDC14A
Target Function
Dual-specificity phosphatase. Required for centrosome separation and productive cytokinesis during cell division. Dephosphorylates SIRT2 around early anaphase. May dephosphorylate the APC subunit FZR1/CDH1, thereby promoting APC-FZR1 dependent degradation of mitotic cyclins and subsequent exit from mitosis. Required for normal hearing.
Target Involvement
Deafness, autosomal recessive, 105 (DFNB105)
Target Subcellular Location
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle. Cell projection, kinocilium. Cell projection, stereocilium.
Target Protein Families
Protein-tyrosine phosphatase family, Non-receptor class CDC14 subfamily
Target Synonyms
CDC14A; Dual specificity protein phosphatase CDC14A; EC 3.1.3.16; EC 3.1.3.48; CDC14 cell division cycle 14 homolog A
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