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| Cat.No | ACP16998 | Target Name | RNF213 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q63HN8 |
|---|
Uniprot Id
Q63HN8
Target Species
Human
Target Name
RNF213
Target Full Name
E3 ubiquitin-protein ligase RNF213
Target Function
E3 ubiquitin-protein ligase involved in angiogenesis. Involved in the non-canonical Wnt signaling pathway in vascular development: acts by mediating ubiquitination and degradation of FLNA and NFATC2 downstream of RSPO3, leading to inhibit the non-canonical Wnt signaling pathway and promoting vessel regression. Also has ATPase activity.
Target Involvement
Moyamoya disease 2 (MYMY2)
Target Subcellular Location
Cytoplasm, cytosol.
Target Protein Families
AAA ATPase family
Target Tissue Specificity
Widely expressed (at protein level).
Target Synonyms
ALK lymphoma oligomerization partner on chromosome 17; C17orf27; Chromosome 17 open reading frame 27; E3 ubiquitin-protein ligase RNF213; FLJ13051; KIAA1554; MGC46622; MGC9929; MYMY2; Mysterin; MYSTR; NET57; RING finger protein 213; RN213_HUMAN; RNF 213; RNF213
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