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Recombinant Human F-box/LRR-repeat protein 15 (FBXL15)

ACP11280

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP11280 Target NameFBXL15
Target SynonymsFBXL15; FBXO37F-box/LRR-repeat protein 15; F-box only protein 37FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-300
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9H469
Background Information
  • Uniprot Id

    Q9H469

  • Target Species

    Human

  • Target Name

    FBXL15

  • Target Full Name

    F-box/LRR-repeat protein 15

  • Target Function

    Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation and bone mass maintenance. Also mediates ubiquitination of SMURF2 and WWP2.

  • Target Subcellular Location

    Cytoplasm.

  • Target Protein Families

    FBXL15 family

  • Target Synonyms

    FBXL15; FBXO37F-box/LRR-repeat protein 15; F-box only protein 37

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