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| Cat.No | ACP11280 | Target Name | FBXL15 |
|---|---|---|---|
| Target Synonyms | FBXL15; FBXO37F-box/LRR-repeat protein 15; F-box only protein 37 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-300 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H469 |
|---|
Uniprot Id
Q9H469
Target Species
Human
Target Name
FBXL15
Target Full Name
F-box/LRR-repeat protein 15
Target Function
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation and bone mass maintenance. Also mediates ubiquitination of SMURF2 and WWP2.
Target Subcellular Location
Cytoplasm.
Target Protein Families
FBXL15 family
Target Synonyms
FBXL15; FBXO37F-box/LRR-repeat protein 15; F-box only protein 37
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