Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
| Cat.No | ACP18170 | Target Name | FOXE3 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-319 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q13461 |
|---|
Uniprot Id
Q13461
Target Species
Human
Target Name
FOXE3
Target Full Name
Forkhead box protein E3
Target Function
Transcription factor that controls lens epithelial cell growth through regulation of proliferation, apoptosis and cell cycle. During lens development, controls the ratio of the lens fiber cells to the cells of the anterior lens epithelium by regulating the rate of proliferation and differentiation. Controls lens vesicle closure and subsequent separation of the lens vesicle from ectoderm. Controls the expression of DNAJB1 in a pathway that is crucial for the development of the anterior segment of the eye.
Target Involvement
Anterior segment dysgenesis 2 (ASGD2); Cataract 34, multiple types (CTRCT34); Aortic aneurysm, familial thoracic 11 (AAT11)
Target Subcellular Location
Nucleus.
Target Synonyms
Drosphilia Forkhead Homolog Like 12; FKHL 12; FKHL12; Forkhead Box E3; Forkhead box protein E3; Forkhead Related Activator 8; Forkhead related protein FKHL12; Forkhead-related protein FKHL12; Forkhead-related transcription factor 8; Foxe3; FOXE3 forkhead box E3 ; FOXE3_HUMAN; FREAC 8; FREAC-8; FREAC8
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
