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Recombinant Human FRAS1-related extracellular matrix protein 2 (FREM2), Truncated

ACP16894

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Specifications

Cat.No	ACP16894	Target Name	FREM2
Target Synonyms	DKFZp781I048; ECM3 homolog; FRAS1-related extracellular matrix protein 2; FREM 2; Frem2; FREM2_HUMAN; KIAA1074	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q5SZK8

Background Information

Uniprot Id

Q5SZK8
Target Species

Human
Target Name

FREM2
Target Full Name

FRAS1-related extracellular matrix protein 2
Target Function

Extracellular matrix protein required for maintenance of the integrity of the skin epithelium and for maintenance of renal epithelia. Required for epidermal adhesion. Involved in the development of eyelids and the anterior segment of the eyeballs.
Target Involvement

Fraser syndrome 2 (FRASRS2)
Target Subcellular Location

Cell membrane; Single-pass type I membrane protein.
Target Protein Families

FRAS1 family
Target Synonyms

DKFZp781I048; ECM3 homolog; FRAS1-related extracellular matrix protein 2; FREM 2; Frem2; FREM2_HUMAN; KIAA1074
Target Background

This gene encodes an integral membrane protein containing numerous CSPG (chondroitin sulfate proteoglycan element) repeats and Calx-beta domains. The encoded protein localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions. This protein is important for the integrity of skin and renal epithelia. Mutations in this gene are associated with Fraser syndrome.

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Recombinant Human FRAS1-related extracellular matrix protein 2 (FREM2), Truncated

Specifications

Immunogen Information

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