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| Cat.No | ACP07267 | Target Name | GPR35 |
|---|---|---|---|
| Target Synonyms | GPR35; G-protein coupled receptor 35; Kynurenic acid receptor; KYNA receptor | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9HC97 |
|---|
Uniprot Id
Q9HC97
Target Species
Human
Target Name
GPR35
Target Full Name
G-protein coupled receptor 35
Target Function
Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Note=Internalized to the cytoplasm after exposure to kynurenic acid.
Target Protein Families
G-protein coupled receptor 1 family
Target Tissue Specificity
Predominantly expressed in immune and gastrointestinal tissues.
Target Synonyms
GPR35; G-protein coupled receptor 35; Kynurenic acid receptor; KYNA receptor
Target Background
Enables C-X-C chemokine receptor activity. Involved in several processes, including chemokine-mediated signaling pathway; negative regulation of voltage-gated calcium channel activity; and positive regulation of cytosolic calcium ion concentration. Is integral component of plasma membrane.
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