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Recombinant Human G-protein coupled receptor 35 (GPR35), Truncated

ACP07267

Number
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Specifications


Cat.No ACP07267 Target NameGPR35
Target SynonymsGPR35; G-protein coupled receptor 35; Kynurenic acid receptor; KYNA receptorFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9HC97
Background Information
  • Uniprot Id

    Q9HC97

  • Target Species

    Human

  • Target Name

    GPR35

  • Target Full Name

    G-protein coupled receptor 35

  • Target Function

    Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins.

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein. Note=Internalized to the cytoplasm after exposure to kynurenic acid.

  • Target Protein Families

    G-protein coupled receptor 1 family

  • Target Tissue Specificity

    Predominantly expressed in immune and gastrointestinal tissues.

  • Target Synonyms

    GPR35; G-protein coupled receptor 35; Kynurenic acid receptor; KYNA receptor

  • Target Background

    Enables C-X-C chemokine receptor activity. Involved in several processes, including chemokine-mediated signaling pathway; negative regulation of voltage-gated calcium channel activity; and positive regulation of cytosolic calcium ion concentration. Is integral component of plasma membrane.

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