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Recombinant Human Glutamate [NMDA] receptor subunit 3A (GRIN3A), Truncated

ACP05905

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Specifications

Cat.No	ACP05905	Target Name	GRIN3A
Target Synonyms	GRIN3A; KIAA1973; Glutamate receptor ionotropic; NMDA 3A; GluN3A; N-methyl-D-aspartate receptor subtype 3A; NMDAR3A; NR3A; NMDAR-L	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q8TCU5

Background Information

Uniprot Id

Q8TCU5
Target Species

Human
Target Name

GRIN3A
Target Full Name

Glutamate receptor ionotropic, NMDA 3A
Target Function

NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine. During the development of neural circuits, plays a role in the synaptic refinement period, restricting spine maturation and growth. By competing with GIT1 interaction with ARHGEF7/beta-PIX, may reduce GIT1/ARHGEF7-regulated local activation of RAC1, hence affecting signaling and limiting the maturation and growth of inactive synapses. May also play a role in PPP2CB-NMDAR mediated signaling mechanism.
Target Subcellular Location

Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane. Cell junction, synapse, postsynaptic density.
Target Protein Families

Glutamate-gated ion channel (TC 1.A.10.1) family, NR3A/GRIN3A subfamily
Target Synonyms

GRIN3A; KIAA1973; Glutamate receptor ionotropic; NMDA 3A; GluN3A; N-methyl-D-aspartate receptor subtype 3A; NMDAR3A; NR3A; NMDAR-L

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Recombinant Human Glutamate [NMDA] receptor subunit 3A (GRIN3A), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Glutamate [NMDA] receptor subunit 3A (GRIN3A), Truncated Now

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