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| Cat.No | ACP18896 | Target Name | GDE1 |
|---|---|---|---|
| Target Synonyms | GDE1; MIR16Glycerophosphodiester phosphodiesterase 1; EC 3.1.4.-; EC 3.1.4.44; Membrane-interacting protein of RGS16; RGS16-interacting membrane protein | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NZC3 |
|---|
Uniprot Id
Q9NZC3
Target Species
Human
Target Name
GDE1
Target Full Name
Glycerophosphodiester phosphodiesterase 1
Target Function
Hydrolyzes the phosphodiester bond of glycerophosphodiesters such as glycerophosphoinositol (GroPIns) and glycerophosphoethanolamine (GroPEth), to yield a glycerol phosphate and an alcohol. Hydrolyzes glycerophospho-N-acylethanolamines to N-acylethanolamines in the brain and partipates to bioactive N-acylethanolamines biosynthesis such as anandamide (an endocannabinoid), N-palmitoylethanolamine (an anti-inflammatory), and N-oleoylethanolamine (an anorexic). In addition, has a lysophospholipase D activity by hydrolyzing N-acyl-lysoplasmenylethanolamine (N-acyl-lysoPlsEt) to N-acylethanolamine. However lysophospholipase D activity is lower than glycerophosphodiester phosphodiesterase activity. Has little or no activity towards glycerophosphocholine.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Target Protein Families
Glycerophosphoryl diester phosphodiesterase family
Target Tissue Specificity
Widely expressed.
Target Synonyms
GDE1; MIR16Glycerophosphodiester phosphodiesterase 1; EC 3.1.4.-; EC 3.1.4.44; Membrane-interacting protein of RGS16; RGS16-interacting membrane protein
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