Recombinant Human Guanine nucleotide-binding protein G (I)/G (S)/G (O) subunit gamma-T2 (GNGT2)

Uniprot Id

O14610

Target Species

Human

Target Name

GNGT2

Target Full Name

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2

Target Function

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

Target Subcellular Location

Cell membrane; Lipid-anchor; Cytoplasmic side.

Target Protein Families

G protein gamma family

Target Tissue Specificity

Retinal cones.

Target Synonyms

GNGT2; GNG8; GNG9; GNGT8Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2; G gamma-C; G-gamma-8; G-gamma-9; Guanine nucleotide binding protein gamma transducing activity polypeptide 2

Target Background

Phototransduction in rod and cone photoreceptors is regulated by groups of signaling proteins. The encoded protein is thought to play a crucial role in cone phototransduction. It belongs to the G protein gamma family and localized specifically in cones. Several transcript variants encoding the same protein have been found for this gene.