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| Cat.No | ACP15738 | Target Name | HFE2 |
|---|---|---|---|
| Target Synonyms | HJV; HFE2; RGMC; Hemojuvelin; Hemochromatosis type 2 protein; Hemojuvelin BMP coreceptor; RGM domain family member C | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 36-400 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6ZVN8 |
|---|
Uniprot Id
Q6ZVN8
Target Species
Human
Target Name
HJV
Target Full Name
Hemojuvelin
Target Function
Acts as a bone morphogenetic protein (BMP) coreceptor. Through enhancement of BMP signaling regulates hepcidin (HAMP) expression and regulates iron homeostasis.
Target Involvement
Hemochromatosis 2A (HFE2A)
Target Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor.
Target Protein Families
Repulsive guidance molecule (RGM) family
Target Tissue Specificity
Adult and fetal liver, heart, and skeletal muscle.
Target Synonyms
HJV; HFE2; RGMC; Hemojuvelin; Hemochromatosis type 2 protein; Hemojuvelin BMP coreceptor; RGM domain family member C
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