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| Cat.No | ACP16991 | Target Name | ERVK-6 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-105 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q69383 |
|---|
Uniprot Id
Q69383
Target Species
Human
Target Name
ERVK-6
Target Full Name
Endogenous retrovirus group K member 6 Rec protein
Target Function
Retroviral replication requires the nuclear export and translation of unspliced, singly-spliced and multiply-spliced derivatives of the initial genomic transcript. Rec interacts with a highly structured RNA element (RcRE) present in the viral 3'LTR and recruits the cellular nuclear export machinery. This permits export to the cytoplasm of unspliced genomic or incompletely spliced subgenomic viral transcripts.
Target Subcellular Location
Cytoplasm. Nucleus, nucleolus. Note=Shuttles between the nucleus and the cytoplasm. When in the nucleus, resides in the nucleolus.
Target Tissue Specificity
Expressed at higher level in placenta, expressed at lower level in several organs and cell lines.
Target Synonyms
ERVK-6; ERVK6; Endogenous retrovirus group K member 6 Rec protein; Central open reading frame; c-orf; cORF; Endogenous retrovirus K protein 6; HERV-K(C7) Rec protein; HERV-K(HML-2.HOM) Rec protein; HERV-K108 Rec protein; HERV-K_7p22.1 provirus Rec protein; K-Rev; Rev-like protein; Rev/Rex homolog
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