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Recombinant Human Insulin-like growth factor-binding protein complex acid labile subunit (IGFALS)

ACP23668

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP23668 Target NameIGFALS
Target SynonymsIGFALS; ALSInsulin-like growth factor-binding protein complex acid labile subunit; ALSFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range28-605
Protein LengthFull Length of Mature ProteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP35858
Background Information
  • Uniprot Id

    P35858

  • Target Species

    Human

  • Target Name

    IGFALS

  • Target Full Name

    Insulin-like growth factor-binding protein complex acid labile subunit

  • Target Function

    Involved in protein-protein interactions that result in protein complexes, receptor-ligand binding or cell adhesion.

  • Target Involvement

    Acid-labile subunit deficiency (ACLSD)

  • Target Subcellular Location

    Secreted, extracellular space.

  • Target Tissue Specificity

    Plasma.

  • Target Synonyms

    IGFALS; ALSInsulin-like growth factor-binding protein complex acid labile subunit; ALS

  • Target Background

    The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene.

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