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Recombinant Human Integrator complex subunit 1 (INTS1), Truncated

ACP06261

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP06261 Target NameINTS1
Target SynonymsINTS1; KIAA1440; UNQ1821/PRO3434; Integrator complex subunit 1; Int1FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8N201
Background Information
  • Uniprot Id

    Q8N201

  • Target Species

    Human

  • Target Name

    INTS1

  • Target Full Name

    Integrator complex subunit 1

  • Target Function

    Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.

  • Target Subcellular Location

    Nucleus membrane; Single-pass membrane protein.

  • Target Protein Families

    Integrator subunit 1 family

  • Target Synonyms

    INTS1; KIAA1440; UNQ1821/PRO3434; Integrator complex subunit 1; Int1

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