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| Cat.No | ACP06253 | Target Name | INTS2 |
|---|---|---|---|
| Target Synonyms | INTS2; KIAA1287; Integrator complex subunit 2; Int2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H0H0 |
|---|
Uniprot Id
Q9H0H0
Target Species
Human
Target Name
INTS2
Target Full Name
Integrator complex subunit 2
Target Function
Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.
Target Subcellular Location
Nucleus membrane; Single-pass membrane protein. Cytoplasm.
Target Protein Families
Integrator subunit 2 family
Target Synonyms
INTS2; KIAA1287; Integrator complex subunit 2; Int2
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