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| Cat.No | ACP10312 | Target Name | IFT122 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9HBG6 |
|---|
Uniprot Id
Q9HBG6
Target Species
Human
Target Name
IFT122
Target Full Name
Intraflagellar transport protein 122 homolog
Target Function
As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is required in ciliogenesis and ciliary protein trafficking. Involved in cilia formation during neuronal patterning. Acts as a negative regulator of Shh signaling. Required to recruit TULP3 to primary cilia.
Target Involvement
Cranioectodermal dysplasia 1 (CED1)
Target Subcellular Location
Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body.
Target Tissue Specificity
Expressed in many tissues. Predominant expression in testis and pituitary.
Target Synonyms
CED; IF122_HUMAN; IFT122; Intraflagellar transport 122 homolog (Chlamydomonas); Intraflagellar transport protein 122 homolog; SPG; WD repeat domain 10; WD repeat-containing protein 10; WD repeat-containing protein 140; WDR10; WDR10p; WDR140
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