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| Cat.No | ACP13734 | Target Name | IFT140 |
|---|---|---|---|
| Target Synonyms | IFT140; KIAA0590; WDTC2; Intraflagellar transport protein 140 homolog; WD and tetratricopeptide repeats protein 2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96RY7 |
|---|
Uniprot Id
Q96RY7
Target Species
Human
Target Name
IFT140
Target Full Name
Intraflagellar transport protein 140 homolog
Target Function
Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs). Plays a pivotal role in proper development and function of ciliated cells through its role in ciliogenesis and/or cilium maintenance. Required for the development and maintenance of the outer segments of rod and cone photoreceptor cells. Plays a role in maintenance and the delivery of opsin to the outer segment of photoreceptor cells.
Target Involvement
Short-rib thoracic dysplasia 9 with or without polydactyly (SRTD9)
Target Subcellular Location
Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium.
Target Synonyms
IFT140; KIAA0590; WDTC2; Intraflagellar transport protein 140 homolog; WD and tetratricopeptide repeats protein 2
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