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| Cat.No | ACP21153 | Target Name | KRTAP5-8 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-187 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O75690 |
|---|
Uniprot Id
O75690
Target Species
Human
Target Name
KRTAP5-8
Target Full Name
Keratin-associated protein 5-8
Target Function
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Target Protein Families
KRTAP type 5 family
Target Tissue Specificity
Restricted to hair root, not detected in any other tissues. Expressed in cuticle layers of differentiating hair follicles.
Target Synonyms
KRTAP5-8; KAP5.8; KRTAP5.8; UHSKB; Keratin-associated protein 5-8; Keratin; ultra high-sulfur matrix protein B; Keratin-associated protein 5.8; UHS keratin B; UHS KerB; Ultrahigh sulfur keratin-associated protein 5.8
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