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Recombinant Human Kinesin-like protein KIF11 (KIF11), Truncated

ACP22805

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP22805 Target NameKIF11
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Protein LengthPartialPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP52732
Background Information
  • Uniprot Id

    P52732

  • Target Species

    Human

  • Target Name

    KIF11

  • Target Full Name

    Kinesin-like protein KIF11

  • Target Function

    Motor protein required for establishing a bipolar spindle during mitosis. Required in non-mitotic cells for transport of secretory proteins from the Golgi complex to the cell surface.

  • Target Involvement

    Microcephaly with or without chorioretinopathy, lymphedema, or mental retardation (MCLMR)

  • Target Subcellular Location

    Cytoplasm. Cytoplasm, cytoskeleton, spindle pole.

  • Target Protein Families

    TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family, BimC subfamily

  • Target Synonyms

    EG5; HKSP; KIF11; KIF11_HUMAN; Kinesin family member 11; Kinesin like protein 1; Kinesin-like protein 1; Kinesin-like protein KIF11; Kinesin-like spindle protein HKSP; Kinesin-related motor protein Eg5; KNSL1; MCLMR; Thyroid receptor-interacting protein 5; TR-interacting protein 5; TRIP-5; TRIP5

  • Target Background

    This gene encodes a motor protein that belongs to the kinesin-like protein family. Members of this protein family are known to be involved in various kinds of spindle dynamics. The function of this gene product includes chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis.

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