Home Products Recombinant Human Lysine-specific demethylase 3B (KDM3B), Truncated

Recombinant Human Lysine-specific demethylase 3B (KDM3B), Truncated

ACP15932

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications

Cat.No	ACP15932	Target Name	KDM3B
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q7LBC6

Background Information

Uniprot Id

Q7LBC6
Target Species

Human
Target Name

KDM3B
Target Full Name

Lysine-specific demethylase 3B
Target Function

Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.
Target Subcellular Location

Nucleus.
Target Protein Families

JHDM2 histone demethylase family
Target Tissue Specificity

Ubiquitous. Highly expressed in placenta, skeletal muscle, kidney, heart and liver.
Target Research Area

Epigenetics and Nuclear Signaling
Target Synonyms

5qNCA; C5orf7; JHDM2B; JmjC domain containing histone demethylation protein 2B; JmjC domain-containing histone demethylation protein 2B; jmjd1b; Jumonji domain containing 1B; Jumonji domain containing protein 1B; Jumonji domain-containing protein 1B; KDM3B; KDM3B_HUMAN; KIAA1082; Lysine (K) specific demethylase 3B ; Lysine-specific demethylase 3B; NET22; Nuclear protein 5qNCA
Target Background

Predicted to enable chromatin DNA binding activity; histone H3-methyl-lysine-9 demethylase activity; and transcription coregulator activity. Predicted to be involved in histone H3-K9 demethylation and regulation of transcription by RNA polymerase II. Located in nucleoplasm. Biomarker of acute lymphoblastic leukemia; breast cancer; colorectal cancer; and lung non-small cell carcinoma.

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Recombinant Human Lysine-specific demethylase 3B (KDM3B), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Lysine-specific demethylase 3B (KDM3B), Truncated Now

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