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| Cat.No | ACP02178 | Target Name | MRGPRD |
|---|---|---|---|
| Target Synonyms | Beta-alanine receptor;G-protein coupled receptor TGR7 | Form | Liquid or Lyophilized powder |
| Expression System | in vitro E.coli expression system | Expression Range | 1-321aa |
| Mol Weight | 42.2 | Protein Length | Full length |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8TDS7 |
|---|
Uniprot Id
Q8TDS7
Target Species
Human
Target Name
MRGPRD
Target Full Name
Mas-related G-protein coupled receptor member D
Target Function
May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Note=Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.
Target Protein Families
G-protein coupled receptor 1 family, Mas subfamily
Target Research Area
Neuroscience
Target Synonyms
MRGPRD; MRGD; Mas-related G-protein coupled receptor member D; Beta-alanine receptor; G-protein coupled receptor TGR7
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