Recombinant Human Matrix metalloproteinase-25 (MMP25)

Cat.No	ACP10601	Target Name	MMP25
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	108-539	Protein Length	Full Length of Mature Protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP10601

Target Name

MMP25

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Expression Range

108-539

Protein Length

Full Length of Mature Protein

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q9NPA2

Background Information

Uniprot Id

Q9NPA2
Target Species

Human
Target Name

MMP25
Target Full Name

Matrix metalloproteinase-25
Target Function

May activate progelatinase A.
Target Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. Secreted, extracellular space, extracellular matrix.
Target Protein Families

Peptidase M10A family
Target Tissue Specificity

Expressed predominantly in leukocytes, lung and spleen. Expressed also in colon carcinoma, astrocytoma and glioblastomas.
Target Research Area

Cancer
Target Synonyms

Leukolysin; matrix metallopeptidase 25; matrix metallopeptidase like 1; matrix metalloproteinase 20; Matrix Metalloproteinase 25; Matrix metalloproteinase 25 precursor; Matrix metalloproteinase-25; Membrane type 6 Matrix Metalloproteinase; Membrane type Matrix Metalloproteinase 6 ; Membrane-type matrix metalloproteinase 6; Membrane-type-6 matrix metalloproteinase; MMP 25; MMP-25; MMP20; MMP20A; MMP25; MMP25_HUMAN; MMPL1; MT MMP 6; MT-MMP 6; MT6 MMP; MT6-MMP; MT6MMP; MTMMP6
Target Background

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25.

Recombinant Human Matrix metalloproteinase-25 (MMP25)

Specifications

Immunogen Information

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