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| Cat.No | ACP09448 | Target Name | MARF1 |
|---|---|---|---|
| Target Synonyms | KIAA0430; Limkain-b1; LKAP; LKAP_HUMAN; MARF1; Meiosis arrest female 1; Meiosis arrest female protein 1; PPP1R34; Protein phosphatase 1; regulatory subunit 34 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9Y4F3 |
|---|
Uniprot Id
Q9Y4F3
Target Species
Human
Target Name
MARF1
Target Full Name
Meiosis regulator and mRNA stability factor 1
Target Function
Essential regulator of oogenesis required for female meiotic progression to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Probably acts via some RNA metabolic process, equivalent to the piRNA system in males, which mediates the repression of transposable elements during meiosis by forming complexes composed of RNAs and governs the methylation and subsequent repression of transposons. Also required to protect from DNA double-strand breaks.
Target Subcellular Location
Peroxisome.
Target Synonyms
KIAA0430; Limkain-b1; LKAP; LKAP_HUMAN; MARF1; Meiosis arrest female 1; Meiosis arrest female protein 1; PPP1R34; Protein phosphatase 1; regulatory subunit 34
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