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This Recombinant Human MYBPC3 protein is a valuable addition to the study of cardiac muscle function. This partial Myosin-binding protein C, cardiac-type (1-328aa) is expressed in an E. coli system, ensuring a consistent and high-quality product for your research endeavors. The N-terminal 6xHis-SUMO tag simplifies protein purification and detection, making it an ideal choice for investigating the function and regulation of cardiac muscle isoform proteins. With a purity of greater than 90% as determined by SDS-PAGE, our Recombinant Human MYBPC3 protein meets the stringent requirements of today's scientific community. Available in both liquid and lyophilized powder forms, this meticulously produced protein supports a wide range of applications, from elucidating the intricate processes of cardiac muscle function to contributing to breakthrough discoveries in cardiovascular research.
This Recombinant Human MYBPC3 protein is a valuable addition to the study of cardiac muscle function. This partial Myosin-binding protein C, cardiac-type (1-328aa) is expressed in an E. coli system, ensuring a consistent and high-quality product for your research endeavors. The N-terminal 6xHis-SUMO tag simplifies protein purification and detection, making it an ideal choice for investigating the function and regulation of cardiac muscle isoform proteins.
With a purity of greater than 90% as determined by SDS-PAGE, our Recombinant Human MYBPC3 protein meets the stringent requirements of today’s scientific community. Available in both liquid and lyophilized powder forms, this meticulously produced protein supports a wide range of applications, from elucidating the intricate processes of cardiac muscle function to contributing to breakthrough discoveries in cardiovascular research.
| Cat.No | ACP02386 | Target Name | MYBPC3 |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | E.coli |
| Expression Range | 1-328aa | Mol Weight | 50.8kDa |
| Protein Length | Partial | Purity | Greater than 90% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q14896 |
|---|
Uniprot Id
Q14896
Target Species
Human
Target Name
MYBPC3
Target Full Name
Myosin-binding protein C, cardiac-type
Target Function
Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.
Target Involvement
Cardiomyopathy, familial hypertrophic 4 (CMH4); Cardiomyopathy, dilated 1MM (CMD1MM); Left ventricular non-compaction 10 (LVNC10)
Target Protein Families
Immunoglobulin superfamily, MyBP family
Target Research Area
Others
Target Synonyms
C protein cardiac muscle isoform; C-protein; cardiac muscle isoform; Cardiac MyBP C; Cardiac MyBP-C; Cardiac myosin binding protein C ; cardiac-type; CMH4; FHC; MYBP C; MYBPC; MYBPC3; Myosin binding protein C cardiac; Myosin binding protein C cardiac-type; Myosin-binding protein C; myosin-binding protein C cardiac type; MYPC3_HUMAN
Target Background
MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3 is expressed exclusively in heart muscle and is a key regulator of cardiac contraction. Mutations in this gene are a frequent cause of familial hypertrophic cardiomyopathy.
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