Recombinant Human Na (+)/H (+) exchange regulatory cofactor NHE-RF1 (SLC9A3R1)

Cat.No	ACP21643	Target Name	SLC9A3R1
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	2-358	Protein Length	Full Length of Mature Protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP21643

Target Name

SLC9A3R1

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Expression Range

2-358

Protein Length

Full Length of Mature Protein

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	O14745

Background Information

Uniprot Id

O14745
Target Species

Human
Target Name

NHERF1
Target Full Name

Na(+)/H(+) exchange regulatory cofactor NHE-RF1
Target Function

Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May enhance Wnt signaling. May participate in HTR4 targeting to microvilli. Involved in the regulation of phosphate reabsorption in the renal proximal tubules. Involved in sperm capacitation. May participate in the regulation of the chloride and bicarbonate homeostasis in spermatozoa
Target Involvement

Nephrolithiasis/osteoporosis, hypophosphatemic, 2 (NPHLOP2)
Target Subcellular Location

Cytoplasm. Apical cell membrane. Endomembrane system; Peripheral membrane protein. Cell projection, filopodium. Cell projection, ruffle. Cell projection, microvillus.
Target Tissue Specificity

Detected in liver, kidney, pancreas, prostate, spleen, small intestine and placenta, in particular in the syncytiotrophoblast.
Target Research Area

Cancer
Target Synonyms

EBP 50; EBP50; Ezrin radixin moesin binding phosphoprotein 50; Ezrin-radixin-moesin-binding phosphoprotein 50; Na(+)/H(+) exchange regulatory cofactor NHE RF; Na(+)/H(+) exchange regulatory cofactor NHE-RF1; Na+/H+ exchange regulatory co factor; NHERF 1; NHERF; NHERF-1; NHERF1; NHRF1_HUMAN; NPHLOP2; Regulatory cofactor of Na(+)/H(+) exchanger; Slc9a3r1; Sodium hydrogen exchanger regulatory factor 1; Sodium-hydrogen exchanger regulatory factor 1; Sodium/hydrogen exchanger regulatory factor 1; Solute carrier family 9 (sodium/hydrogen exchanger) member 3 regulator 1; Solute carrier family 9 (sodium/hydrogen exchanger); isoform 3 regulatory factor 1; Solute carrier family 9 isoform 3 regulatory factor 1; Solute carrier family 9 isoform A3 regulatory factor 1; Solute carrier family 9 member 3 regulator 1

Recombinant Human Na (+)/H (+) exchange regulatory cofactor NHE-RF1 (SLC9A3R1)

Specifications

Immunogen Information

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