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Recombinant Human Neuronal membrane glycoprotein M6-a (GPM6A), Truncated

ACP06945

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Specifications

Cat.No	ACP06945	Target Name	GPM6A
Target Synonyms	GPM6A; M6A; Neuronal membrane glycoprotein M6-a; M6a	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	P51674

Background Information

Uniprot Id

P51674
Target Species

Human
Target Name

GPM6A
Target Full Name

Neuronal membrane glycoprotein M6-a
Target Function

Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
Target Subcellular Location

Cell membrane; Multi-pass membrane protein. Cell projection, axon. Cell projection, growth cone. Cell projection, dendritic spine. Cell projection, filopodium. Cell projection, neuron projection.
Target Protein Families

Myelin proteolipid protein family
Target Synonyms

GPM6A; M6A; Neuronal membrane glycoprotein M6-a; M6a
Target Background

Predicted to enable calcium channel activity. Involved in neuron migration and stem cell differentiation. Located in extracellular exosome.

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Recombinant Human Neuronal membrane glycoprotein M6-a (GPM6A), Truncated

Specifications

Immunogen Information

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