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| Cat.No | ACP12739 | Target Name | RAET1E |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8TD07 |
|---|
Uniprot Id
Q8TD07
Target Species
Human
Target Name
RAET1E
Target Full Name
Retinoic acid early transcript 1E
Target Function
Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.
Target Subcellular Location
Membrane; Single-pass type I membrane protein.; [Isoform 4]: Secreted.
Target Protein Families
MHC class I family
Target Tissue Specificity
Predominantly expressed in the skin, but also expressed in testis and trachea. Up-regulated in tumor cells of different origins. Expression progressively decreased after treatment of tumor cells with retinoic acid.
Target Synonyms
bA350J20.7; LETAL; Lymphocyte effector toxicity activation ligand; MGC125308; MGC125309; N2DL-4; N2DL4; N2DL4_HUMAN; NKG2D ligand 4; NKG2D ligand 4 precursor; NKG2DL4; RAE-1-like transcript 4; RAET1E; RAET1E2; Retinoic acid early transcript 1E; RL-4
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