Home Products Recombinant Human Nuclear pore complex protein Nup214 (NUP214), Truncated

Recombinant Human Nuclear pore complex protein Nup214 (NUP214), Truncated

ACP23528

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Specifications

Cat.No	ACP23528	Target Name	NUP214
Target Synonyms	214 kDa nucleoporin; CAIN; CAN; CAN protein putative oncogene; D9S46E; N214; NU214_HUMAN; Nuclear pore complex protein Nup214; nucleoporin 214kDa; Nucleoporin Nup214; Nup214; p250; Protein CAN	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	P35658

Background Information

Uniprot Id

P35658
Target Species

Human
Target Name

NUP214
Target Full Name

Nuclear pore complex protein Nup214
Target Function

Part of the nuclear pore complex. Has a critical role in nucleocytoplasmic transport. May serve as a docking site in the receptor-mediated import of substrates across the nuclear pore complex.; (Microbial infection) Required for capsid disassembly of the human adenovirus 5 (HadV-5) leading to release of the viral genome to the nucleus (in vitro).
Target Involvement

A chromosomal aberration involving NUP214 is found in a subset of acute myeloid leukemia (AML); also known as acute non-lymphocytic leukemia. Translocation t(6;9)(p23;q34) with DEK. It results in the formation of a DEK-CAN fusion gene.
Target Subcellular Location

Nucleus, nuclear pore complex.
Target Tissue Specificity

Expressed in thymus, spleen, bone marrow, kidney, brain and testis, but hardly in all other tissues or in whole embryos during development.
Target Synonyms

214 kDa nucleoporin; CAIN; CAN; CAN protein putative oncogene; D9S46E; N214; NU214_HUMAN; Nuclear pore complex protein Nup214; nucleoporin 214kDa; Nucleoporin Nup214; Nup214; p250; Protein CAN

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Recombinant Human Nuclear pore complex protein Nup214 (NUP214), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Nuclear pore complex protein Nup214 (NUP214), Truncated Now

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