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| Cat.No | ACP13645 | Target Name | NUP43 |
|---|---|---|---|
| Target Synonyms | NUP43Nucleoporin Nup43; Nup107-160 subcomplex subunit Nup43; p42 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-380 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8NFH3 |
|---|
Uniprot Id
Q8NFH3
Target Species
Human
Target Name
NUP43
Target Full Name
Nucleoporin Nup43
Target Function
Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation.
Target Subcellular Location
Chromosome, centromere, kinetochore. Nucleus, nuclear pore complex.
Target Synonyms
NUP43Nucleoporin Nup43; Nup107-160 subcomplex subunit Nup43; p42
Target Background
Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP43 is part of one such subcomplex, Nup107-160 (Loiodice et al., 2004 [PubMed 15146057]).
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